Histone deacetylase 8 interacts with the GTPase SmRho1 in Schistosoma mansoni
Lucile Pagliazzo, Stéphanie Caby, Julien Lancelot…·Raymond John Pierce
This study identifies SmHDAC8 as involved in cytoskeleton organization through its interaction with SmRho1 isoforms in Schistosoma mansoni, showing acetylation of SmRho1 and disruption of actin cytoskeleton upon SmHDAC8 inhibition.