Author

Katherine A. White

Sanford ResearchORCID 0000-0002-1663-1961Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 6

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Organism:mouse· 3 Research Focus:cell type annotation· 2 Organism:non-human primate· 2 Research Focus:benchmarking· 1 Research Focus:database / resource· 1 Research Focus:differential expression· 1 Assay:protein sequence· 1

Frequent Co-Authors

Jill M. WeimeriD· 6 shared Jon J. BrudvigiD· 4 shared Brandon L. MeyerinkiD· 3 shared Rajesh KhannaiD· 3 shared Tyler B. JohnsoniD· 3 shared Vicki J. SwieriD· 3 shared Aude ChefdevilleiD· 2 shared Christopher S. RogersiD· 2 shared

Activity by Year

2018-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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6 shared papersNeuroscience

Jill M. WeimerORCID

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Author profile →

6 papers

Recent·Most cited

Sortilin inhibition treats multiple neurodegenerative lysosomal storage disorders.

Hannah G. Leppert, Joelle T. Anderson, Kaylie J. Timm, Cristina Davoli, Melissa A. Pratt, Clarissa D. Booth, Katherine A. White, Mitchell J. Rechtzigel, Brandon L. Meyerink, Tyler B. Johnson, Jon J. Brudvig, Jill M. Weimer

This study shows that sortilin inhibition with AF38469 improves lysosomal and glial pathology in multiple Batten disease models.

bioRxiv · Sep 22, 2023 · PreprintNeuroscience

A novel porcine model of CLN3 Batten disease recapitulates clinical phenotypes

Vicki J. Swier, Katherine A. White, Tyler B. Johnson, Xiaojun Wang, Jimin Han, David A. Pearce, Ruchira Singh, Arlene V. Drack, Wanda L. Pfeifer, Christopher S. Rogers, Jon J. Brudvig, Jill M. Weimer

This paper presents a novel porcine model of CLN3 Batten disease that recapitulates clinical phenotypes observed in humans.

Disease Models & Mechanisms · Jun 12, 2023Peer-reviewedNeuroscience

A CLN6-CRMP2-KLC4 complex regulates anterograde ER-derived vesicle trafficking in cortical neurites

SY Koh, JT Cain, Helen Magee, Katherine A. White, Mitchell J. Rechtzigel, Brandon L. Meyerink, Hannah G. Leppert, DJ Timm, JP Morgan, TB Johnson, Bryon D. Grove, Rajesh Khanna, Kenneth Hensley, Jon J. Brudvig, Jill M. Weimer

This study identifies a novel CCK complex involving CLN6, CRMP2, and KLC4 that regulates ER-derived vesicle transport in axons, with implications for neurodegenerative disease therapy.

bioRxiv · Sep 16, 2021 · PreprintNeuroscience

AAV9 gene therapy restores lifespan and treats pathological and behavioral abnormalities in a mouse model of CLN8-Batten disease

Tyler B. Johnson, Katherine A. White, Jon J. Brudvig, Jacob T. Cain, Logan M. Langin, Melissa A. Pratt, Clarissa D. Booth, Derek J. Timm, Samantha S. Davis, Brandon L. Meyerink, Shibi B. Likhite, Kathrin Meyer, Jill M. Weimer

This study shows that AAV9 gene therapy in a mouse model of CLN8-Batten disease improves lifespan, reduces pathology, and reverses behavioral issues.

Molecular Therapy · Sep 24, 2020Peer-reviewedNeuroscience

Validating indicators of CNS disorders in a swine model of neurological disease

Vicki J. Swier, Katherine A. White, David Kyle Meyerholz, Aude Chefdeville, Rajesh Khanna, Jessica C. Sieren, Dawn E. Quelle, Jill M. Weimer

The paper validates CNS-related antibodies in a miniswine model of neurofibromatosis type 1 to support translational research.

PLoS ONE · Feb 19, 2020Peer-reviewedNeuroscience

Sex-dependent differences in pain and sleep in a porcine model of Neurofibromatosis type 1

Rajesh Khanna, Aubin Moutal, Katherine A. White, Aude Chefdeville, Pedro Negrao de Assis, Song Cai, Vicki J. Swier, Shreya Sai Bellampalli, Marissa D. Giunta, Benjamin W. Darbro, Dawn E. Quelle, Jessica C. Sieren, Margaret R. Wallace, Christopher S. Rogers, David Kyle Meyerholz, Jill M. Weimer

This study characterizes pain and sleep behaviors in a porcine model of NF1, identifying sex-dependent differences and potential therapeutic targets.

bioRxiv · Dec 20, 2018 · PreprintNeuroscience