Bastiaan B.J. Tops

Ultra-fast deep-learned pediatric CNS tumor classification during surgery

This paper develops a deep learning model for intraoperative pediatric CNS tumor classification using rapid sequencing, achieving accurate results within 60-90 minutes.

Systematic discovery of gene fusions in pediatric cancer by integrating RNA-seq and WGS

This paper develops a method to detect tumor-specific gene fusions in pediatric cancer by integrating RNA-seq and WGS, identifying 165 high-confidence fusions and their structural variants.

Trecode: a FAIR eco-system for the analysis and archiving of omics data in a combined diagnostic and research setting

Trecode provides a FAIR-compliant platform for managing and analyzing omics data in clinical and research settings, ensuring reproducibility and data reuse.

Distribution of GOPC:ROS1 and other ROS1 fusions in glioma types

The paper identifies ROS1 fusions in various glioma types through genomic and transcriptomic analysis, showing they are not restricted to specific subtypes.

Micro-costing Diagnostics in Oncology: From Single-Gene Testing to Whole Genome Sequencing

This study compares the costs of various diagnostic techniques, including whole genome sequencing, for treating specific cancers in the Netherlands.