Guoji Guo

This paper introduces UURNA-seq, a high-throughput single-nucleus RNA sequencing method, and constructs a comprehensive obesity atlas revealing transcriptional changes and metabolic pathway dysregulation.

The paper identifies 202 variable gene regulatory networks and predicts essential regulators for over 800 cell types in the mouse using the mouse cell atlas data.

This paper discusses challenges and future directions in single-cell analysis, highlighting advances in technologies and computational methods for studying cellular heterogeneity.

The paper develops Microwell-seq, a high-throughput scRNA-seq platform, to construct a single-cell resolution transcriptome atlas of human hematopoietic differentiation, revealing a revised hierarchy without oligopotent progenitors.