Gabriel A. Kwong

This paper introduces a multimodal microscope that uses a cGAN to generate virtual fluorescence images from phase contrast data, enabling virtual histological staining of bulk tissues.

This paper introduces MOSH, a multiscale optical super-resolution histology platform that enhances resolution while maintaining tissue-scale context and throughput.

This study develops SynNotch reporters to visualize force transmission and downstream signaling in immunoreceptors in vivo, showing force acts as a co-stimulus for CD40 and TCR signaling.

This paper develops a high-throughput method to identify and characterize neutralizing antibodies in vaccinated rhesus macaques, revealing key features of effective antibody responses.

This paper introduces OncoSCOUT, a method using engineered T cells with protease-activatable receptors to detect early-stage cancer with improved sensitivity compared to existing biomarkers.

This paper introduces qOBM for non-destructive, label-free monitoring of T cell cultures, showing strong correlation with traditional assays and potential for improving cell therapy development.

This paper introduces deep-ultraviolet microscopy for non-destructive T cell characterization and subtyping, showing high accuracy in viability, activation state, and subtype classification.

This study demonstrates closed-loop sonothermogenetic control of CAR T cells to achieve metronomic activation in brain tumors without harming healthy tissue.

This paper develops antigen-presenting nanoparticles (APNs) for in vivo mRNA delivery to engineer Ag-specific T cells, showing efficacy in mouse models of type 1 diabetes and multiple myeloma.