Author

Patricio Marcelo Polanco

The University of Texas Southwestern Medical CenterORCID 0000-0002-1719-1208Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell-cell communication· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Approach:experimental assay· 1

Frequent Co-Authors

Alex C. KimiD· 2 shared Huocong HuangiD· 2 shared Xiongfeng CheniD· 2 shared Zhuan ZhouiD· 2 shared Alessandro La FerlitaiD· 1 shared Aslam M. EjaziD· 1 shared Bo ZhangiD· 1 shared Francesca RossiiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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2 shared papersCancer Biology

Alex C. KimORCID

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2 papers

Recent·Most cited

Cancer BiologyCancer CellPeer-reviewedSep 25, 2025

✦ In-depth digest

Single-cell resolution spatial analysis of antigen-presenting cancer-associated fibroblast niches

Xiongfeng Chen, Zhuan Zhou, Luyu Xie…·Huocong Huang

Pan-cancer single-cell and spatial profiling resolves two antigen-presenting CAF lineages: tumor-adjacent mesothelial-like apCAFs and tertiary lymphoid structure-associated fibrocyte-like apCAFs, both secreting pro-tumorigenic SPP1.

63 citationstop 1%

humanmouse

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Cancer BiologybioRxivPreprintApr 11, 2025

TWIST1 mediated transcriptional activation of SPON2 drives colorectal peritoneal metastasis through activation of cancer-associated fibroblast signaling network

Zhuan Zhou, Alessandro La Ferlita, Manoj H. Palavalli…·Alex C. Kim

This study identifies the SPP1-TWIST1-SPON2 signaling axis as a driver of colorectal peritoneal metastasis through cancer-associated fibroblast signaling.

DOI 10.1101/2025.04.11.648429

humanbulk RNA-seq

𝕏 PostBluesky