Author

Katharina Held

VIB-KU Leuven Center for Brain & Disease ResearchORCID 0000-0002-1727-9517Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Organism:mouse· 1

Frequent Co-Authors

Alina MiliciiD· 1 shared Ana Cristina Nogueira FreitasiD· 1 shared Annelies JanssensiD· 1 shared Ariel Talavera· 1 shared Evelien Van HoeymisseniD· 1 shared Joris VriensiD· 1 shared Justyna B. StartekiD· 1 shared Karel TalaveraiD· 1 shared

Activity by Year

2020-2026 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 16 mutual co-author links

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1 shared paperPharmacology & Toxicology

Alina MiliciORCID

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2 papers

Recent·Most cited

Pharmacology & ToxicologybioRxivPreprintMay 12, 2026

Activation by statins unveils two putative agonist binding sites in the pore domain of TRPA1

Justyna B. Startek, Alina Milici, Katharina Held…·Karel Talavera

This study identifies two distinct agonist binding sites in TRPA1 activated by statins and shows competitive interactions between agonists and antagonists.

DOI 10.64898/2026.05.08.723702

humanmouse

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NeuroscienceeLifePeer-reviewedMay 19, 2020

Gain of channel function and modified gating properties in TRPM3 mutants causing intellectual disability and epilepsy

Evelien Van Hoeymissen, Katharina Held, Ana Cristina Nogueira Freitas…·Joris Vriens

This study investigates two TRPM3 mutations linked to DEE, showing they cause gain of function through altered channel gating and increased sensitivity to neurosteroids and heat.

58 citations

humanexperimental assay

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