Author

Ariel Talavera

Université Libre de Bruxelles

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Pharmacology & Toxicology· 2 Microbiology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:human· 2 Research Focus:cell type annotation· 1 Organism:E. coli· 1 Assay:electronic health records· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Abel García-PinoiD· 2 shared Hedvig TammaniD· 2 shared Karel TalaveraiD· 2 shared Katleen Van NeromiD· 2 shared Vasili HauryliukiD· 2 shared Alejandro López‐RequenaiD· 1 shared Alina MiliciiD· 1 shared Andres AineloiD· 1 shared

Activity by Year

2019-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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2 shared papersMicrobiology

Abel García-PinoORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Cinnamaldehyde interacts with the local anesthetic pocket of the NaV 1.5 channel

Julio Alvarez‐Collazo, Alejandro López‐Requena, Ariel Talavera, Julio L. Álvarez, Karel Talavera

This study shows that cinnamaldehyde blocks NaV1.5 channels in a voltage-dependent manner, similar to local anesthetics, and identifies key residues involved in this interaction.

bioRxiv · Sep 18, 2026 · PreprintPharmacology & Toxicology

Activation by statins unveils two putative agonist binding sites in the pore domain of TRPA1

Justyna B. Startek, Alina Milici, Katharina Held, Ariel Talavera, Karel Talavera

This study identifies two distinct agonist binding sites in TRPA1 activated by statins and shows competitive interactions between agonists and antagonists.

bioRxiv · May 12, 2026 · PreprintPharmacology & Toxicology

Nanobody-mediated modulation of long RSH enzymes Rel and RelA catalysis by restriction of their conformational landscape

Katleen Van Nerom, Andres Ainelo, Kyo Coppieters ’t Wallant, Ariel Talavera, Dannele Echemendia-Blanco, Sarah Peeters, Brahim El Khalfaoui Oulali, Hedvig Tamman, Tatsuaki Kurata, Mohammad Roghanian, Chloé Martens, Els Pardon, Jan Steyaert, Vasili Hauryliuk, Abel García-Pino

This study identifies nanobodies that modulate Rel and RelA enzyme activity by trapping them in specific conformational states, inhibiting (p)ppGpp synthesis and affecting bacterial virulence.

bioRxiv · Aug 7, 2025 · PreprintMicrobiology

Nucleotide-mediated allosteric regulation of bifunctional Rel enzymes

Hedvig Tamman, Katleen Van Nerom, Hiraku Takada, Niels Vandenberk, Daniel Scholl, Yury S. Polikanov, Johan Hofkens, Ariel Talavera, Vasili Hauryliuk, Jelle Hendrix, Abel García-Pino

This study reveals a guanosine-switch mechanism that regulates the opposing activities of bifunctional Rel enzymes through allosteric changes.

bioRxiv · Jun 13, 2019 · PreprintMolecular Biology