Maili Liu

High-resolution NMR spectroscopy of proteins in intact mitochondria

The paper uses high-resolution NMR spectroscopy to study protein interactions and modifications within intact mitochondria, providing insights into mitochondrial protein function and stability.

Characterizing Tyrosine Ring Flips in Proteins by 19F NMR

This paper introduces two novel 19F NMR probes to study tyrosine ring-flip dynamics in proteins, showing they can quantify and modulate these motions in vitro and in living cells.

ATAD2 BRD mediates liquid-liquid phase separation of ATAD2 to promote histone acetylation

This study shows that the ATAD2 BRD mediates liquid-liquid phase separation to enhance histone acetylation and promote gene expression.

A Regulatory Role of Molecular Chaperones in Excited States and Functions of Folded Enzymes

This study shows chaperones modulate enzyme activity in native states, expanding their role beyond protein folding.

NMR-guided rational exploration of co-factors in boosting the Pfu DNA polymerase

The paper identifies two co-factors that enhance Pfu DNA polymerase performance using NMR-based hot spot residue screening without prior structural data.

Functional Hotspots Identification via a Hybrid NMR-Computational Approach Facilitating Directed Evolution of Large Enzyme

This paper identifies functional hotspots in large enzymes using a hybrid NMR-computational approach, enabling efficient directed evolution with targeted mutagenesis.

Oligopeptide (FK)4 facilitates the determination of the absolute stereochemistry of chiral organic compounds via NMR Spectroscopy

This study demonstrates how the oligopeptide (FK)4 enables the determination of absolute stereochemistry of chiral compounds using NMR spectroscopy by combining alignment medium and chiral differentiating properties.