Author

Sivaraman Padavattan

National Institute of Mental Health and NeurosciencesORCID 0000-0002-1732-5421Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 2 Biophysics· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:chromatin & epigenetic regulation· 2 Approach:experimental assay· 2 Assay:imaging· 2 Assay:proteomics· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Sangeeta NathiD· 3 shared Archanalakshmi KambaruiD· 2 shared B. K. Anirudh SreenivasiD· 2 shared Abinaya RaghavaniD· 1 shared Ashok Ravula· 1 shared Balasundaram PadmanabhaniD· 1 shared Jiřı́ NeužiliD· 1 shared M R VarshithiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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3 shared papersCell Biology

Sangeeta NathORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Cell BiologyCell & BiosciencePeer-reviewedJul 5, 2026

α-Synuclein Triggers Intercellular Nanotubes Formation to Prevent Apoptosis in Astroglia by Promoting Stemness

Rachana Kashyap, B. K. Anirudh Sreenivas, M R Varshith…·Sangeeta Nath

This study shows that α-synuclein protofibrils induce tunneling nanotubes in astrocytes, promoting stemness and apoptosis resistance through pFAK-Nanog interaction and p53 degradation.

DOI 10.1186/s13578-026-01617-9

mousehuman

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Cell BiologybioRxivPreprintMar 16, 2026

Mechanical Signaling Drives Tunneling Nanotubes to Preserve Cytoskeleton Tension and Lamin Integrity Against α-Synuclein-Induced Senescence in Astroglia

Suchana Chatterjee, Ashok Ravula, B. K. Anirudh Sreenivas…·Sangeeta Nath

This study shows that tunneling nanotubes (TNTs) in astroglia maintain cytoskeleton tension and lamin integrity to counteract α-synuclein-induced senescence.

DOI 10.64898/2026.03.13.711517

humanimaging

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BiophysicsCommunications BiologyPeer-reviewedMay 8, 2025

Structural and functional insights into nuclear role of Parkinson's Disease-associated α-Synuclein

Sneha Jos, Archanalakshmi Kambaru, T.K. Prasad…·Sivaraman Padavattan

This study identifies how Parkinson's Disease-associated α-Synuclein interacts with histone dimers, revealing structural and functional insights into its role in chromatin regulation.

8 citations

humanproteomics

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