Author

Archanalakshmi Kambaru

National Institute of Mental Health and NeurosciencesORCID 0000-0003-1795-0080Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biophysics· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:chromatin & epigenetic regulation· 2 Organism:human· 2 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Assay:imaging· 1

Frequent Co-Authors

Sangeeta NathiD· 2 shared Sivaraman PadavattaniD· 2 shared B. K. Anirudh SreenivasiD· 1 shared Balasundaram PadmanabhaniD· 1 shared Jiřı́ NeužiliD· 1 shared M R VarshithiD· 1 shared Neelagandan KamariahiD· 1 shared Rachana Kashyap· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersCell Biology

Sangeeta NathORCID

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2 papers

Recent·Most cited

Cell BiologyCell & BiosciencePeer-reviewedJul 5, 2026

α-Synuclein Triggers Intercellular Nanotubes Formation to Prevent Apoptosis in Astroglia by Promoting Stemness

Rachana Kashyap, B. K. Anirudh Sreenivas, M R Varshith…·Sangeeta Nath

This study shows that α-synuclein protofibrils induce tunneling nanotubes in astrocytes, promoting stemness and apoptosis resistance through pFAK-Nanog interaction and p53 degradation.

DOI 10.1186/s13578-026-01617-9

mousehuman

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BiophysicsCommunications BiologyPeer-reviewedMay 8, 2025

Structural and functional insights into nuclear role of Parkinson's Disease-associated α-Synuclein

Sneha Jos, Archanalakshmi Kambaru, T.K. Prasad…·Sivaraman Padavattan

This study identifies how Parkinson's Disease-associated α-Synuclein interacts with histone dimers, revealing structural and functional insights into its role in chromatin regulation.

8 citations

humanproteomics

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