Author

B. K. Anirudh Sreenivas

Manipal Academy of Higher EducationORCID 0000-0002-5845-8693Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:imaging· 2 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1 Assay:metabolomics· 1

Frequent Co-Authors

Sangeeta NathiD· 2 shared Sivaraman PadavattaniD· 2 shared Abinaya RaghavaniD· 1 shared Archanalakshmi KambaruiD· 1 shared Ashok Ravula· 1 shared Jiřı́ NeužiliD· 1 shared M R VarshithiD· 1 shared Niharika Shivanandaswamy· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersCell Biology

Sangeeta NathORCID

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2 papers

Recent·Most cited

α-Synuclein Triggers Intercellular Nanotubes Formation to Prevent Apoptosis in Astroglia by Promoting Stemness

Rachana Kashyap, B. K. Anirudh Sreenivas, M R Varshith, Rajashri Rameshwar Mundada, Sreedevi Padmanabhan, Shreshta Jain, Archanalakshmi Kambaru, Somasish Ghosh Dastidar, Sivaraman Padavattan, Vinay Kumar Rao, Ravi R. Manjithaya, Jiřı́ Neužil, Sangeeta Nath

This study shows that α-synuclein protofibrils induce tunneling nanotubes in astrocytes, promoting stemness and apoptosis resistance through pFAK-Nanog interaction and p53 degradation.

Cell & Bioscience · Jul 5, 2026Peer-reviewedCell Biology

Mechanical Signaling Drives Tunneling Nanotubes to Preserve Cytoskeleton Tension and Lamin Integrity Against α-Synuclein-Induced Senescence in Astroglia

Suchana Chatterjee, Ashok Ravula, B. K. Anirudh Sreenivas, Abinaya Raghavan, Niharika Shivanandaswamy, Sivaraman Padavattan, Sreenath Balakrishnan, Sangeeta Nath

This study shows that tunneling nanotubes (TNTs) in astroglia maintain cytoskeleton tension and lamin integrity to counteract α-synuclein-induced senescence.

bioRxiv · Mar 16, 2026 · PreprintCell Biology