Sarah M. O’Keefe

Rapid plastid isolation reveals the chloroplast proteome and structures of the chlororibosome large subunit and RuBisCO in Marchantia polymorpha

This study isolates plastids from Marchantia polymorpha and determines their proteome and high-resolution structures of chlororibosome and RuBisCO, revealing structural conservation and functional insights.

Intrinsic errors in mitochondrial translation trigger a decline in cell fitness.

This study shows that errors in mitochondrial translation cause cellular stress and metabolic changes linked to disease and aging, independent of oxidative phosphorylation.