Author

Diego Galeano

Fundação Getulio VargasORCID 0000-0002-1748-7148Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 4 Systems Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 4 Organism:human· 3 Assay:bulk RNA-seq· 2 Approach:statistical model· 2 Research Focus:differential expression· 1 Approach:experimental assay· 1 Approach:machine learning (classical)· 1 Approach:matrix factorization· 1

Frequent Co-Authors

Alberto PaccanaroiD· 4 shared Afshin BeheshtiiD· 2 shared Amanda Saravia-ButleriD· 2 shared Christopher E. MasoniD· 2 shared Deanne M. TayloriD· 2 shared Douglas C. WallaceiD· 2 shared Eve Syrkin WurteleiD· 2 shared Francisco J. EnguitaiD· 2 shared

Activity by Year

2019-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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4 shared papersBioinformatics

Alberto PaccanaroORCID

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

The interplay between lncRNAs, RNA-binding proteins and viral genome during SARS-CoV-2 infection reveals strong connections with regulatory events involved in RNA metabolism and immune response.

Francisco J. Enguita, Ana Lúcia Leitão, John Tyson McDonald, Victoria Zaksas, Saswati Das, Diego Galeano, Deanne M. Taylor, Eve Syrkin Wurtele, Amanda Saravia-Butler, Stephen B. Baylin, Robert Meller, David Marshall Porterfield, Douglas C. Wallace, Jonathan Cummings Schisler, Christopher E. Mason, Afshin Beheshti

The paper identifies a lncRNA signature associated with SARS-CoV-2 infection through transcriptomic analysis and functional correlation studies.

bioRxiv · Mar 26, 2022 · PreprintBioinformatics

The Great Deceiver: miR-2392's Hidden Role in Driving SARS-CoV-2 Infection

Jackie McDonald, Francisco J. Enguita, Deanne M. Taylor, Robert J. Griffin, Waldemar Priebe, Mark R. Emmett, Mohammad M. Sajadi, Anthony D. Harris, Jean Clement, Joseph M. Dybas, Nükhet Aykin‐Burns, Joseph W. Guarnieri, Larry N. Singh, Peter W. Grabham, Stephen B. Baylin, , Afshin Beheshti

The paper identifies miR-2392 as a miRNA involved in SARS-CoV-2 infection, showing its role in inflammation, glycolysis, and hypoxia, and develops a miRNA-based therapeutic targeting it.

bioRxiv · Apr 23, 2021 · PreprintSystems Biology

Interpretable Drug Target Predictions using Self-Expressiveness

Diego Galeano, Santiago Noto, Ruben Jimenez, Alberto Paccanaro

Inception predicts missing drug-target interactions using an interpretable self-expressive model, outperforming existing methods in cross-validation and prospective testing.

bioRxiv · Mar 1, 2021 · PreprintBioinformatics

The Geometric Sparse Matrix Completion Model for Predicting Drug Side effects

Diego Galeano, Alberto Paccanaro

The paper introduces a matrix completion model to predict drug side effects using pharmacological side information, achieving better performance than existing methods with explainable predictions.

bioRxiv · May 29, 2019 · PreprintBioinformatics

Predicting the Frequency of Drug Side effects

Diego Galeano, Alberto Paccanaro

A novel explainable machine learning algorithm predicts the frequency of drug side effects in the population.

bioRxiv · Mar 31, 2019 · PreprintBioinformatics