Author

Sofie Vandendriessche

Rega Institute for Medical ResearchORCID 0000-0002-1756-748XUnclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Sofie Vandendriessche1 paper · Rega Institute for Medical Research

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Pedro Elias MarquesiD· 2 shared Annet van de Waterweg BerendsiD· 1 shared Emilia Laura BialekiD· 1 shared Jana Van BroeckhoveniD· 1 shared Janne Renders· 1 shared Jeroen F. J. BogieiD· 1 shared Lotte Vanbrabant· 1 shared Matheus Silvério MattosiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersImmunology

Pedro Elias MarquesORCID

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2 papers

Recent·Most cited

ImmunologybioRxivPreprintMay 5, 2026

Internalization of myelin debris by neutrophils fuels inflammation

Mirre De Bondt, Janne Renders, Yana Sterckx…·Sofie Struyf

The paper shows human neutrophils internalize myelin debris via complement receptor 3, leading to a pro-inflammatory phenotype in MS.

DOI 10.64898/2026.04.30.722078

humanbulk RNA-seq

𝕏 PostBluesky

ImmunologyFrontiers in ImmunologyPeer-reviewedDec 17, 2024

Complement activation at injury sites drives the phagocytosis of necrotic cell debris and resolution of liver injury

Sofie Vandendriessche, Matheus Silvério Mattos, Emilia Laura Bialek…·Pedro Elias Marques

This study shows that complement proteins C1q and C3b promote phagocytosis of necrotic debris by neutrophils, monocytes, and macrophages, which is essential for liver injury resolution.

19 citations

𝕏 PostBluesky