Pedro Elias Marques

The paper shows human neutrophils internalize myelin debris via complement receptor 3, leading to a pro-inflammatory phenotype in MS.

This study identifies phosphatidylethanolamine (PE) as a phagocytic ligand recognized by CD300 receptors, facilitating the uptake of apoptotic cells and microbial extracellular vesicles.

This study shows that enzymatic degradation of necrotic debris improves recovery after liver injury, while disassembly strategies like peptide treatment or plasmin activation are less effective or harmful.

This study identifies CCR2 as critical for monocyte recruitment and BBB disruption in USUV encephalitis, showing therapeutic benefit from glucocorticoid treatment.

This study shows that complement proteins C1q and C3b promote phagocytosis of necrotic debris by neutrophils, monocytes, and macrophages, which is essential for liver injury resolution.