BioinformaticsFrontiers in ImmunologyPeer-reviewed
Large-scale template-based structural modeling of T-cell receptors with known antigen specificity reveals complementarity features.
Dmitrii S. Shcherbinin, Vadim K Karnaukhov, Ivan V. Zvyagin…·Mikhail Shugay
The paper uses template-based modeling to generate TCR:antigen:MHC structures and identifies amino acid contact features that influence antigen recognition.