Author

Grace E. Lidgerwood

The University of MelbourneORCID 0000-0002-1774-5944Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:differential expression· 5 Organism:human· 5 Approach:statistical model· 5 Research Focus:gene regulatory network inference· 3 Assay:scRNA-seq· 3 Research Focus:benchmarking· 2 Assay:bulk RNA-seq· 2 Assay:proteomics· 2

Frequent Co-Authors

Alex William HewittiD· 5 shared Alice PébayiD· 5 shared Joseph E. PowelliD· 5 shared Maciej DaniszewskiiD· 5 shared Anne SenabouthiD· 4 shared Damián HernándeziD· 4 shared Helena Hai LiangiD· 4 shared Chia‐Ling ChaniD· 3 shared

Activity by Year

2021-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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5 shared papersGenetics

Alex William HewittORCID

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Patient induced pluripotent stem cells identify specificities of a reticular pseudodrusen phenotype in age-related macular degeneration

Jenna C. Hall, Kavitha Krishna Sudhakar, Maciej Daniszewski, Anne Senabouth, Carla J. Abbott, Helena Hai Liang, Himeesh Kumar, Grace E. Lidgerwood, Mehdi Mirzaei, Jessica Yuen Wuen Ma, Trevor Atkeson, Yumiko Hirokawa, Emeline F. Nandrot, Alexander Barnett, Chantal Cazevieille, , Alice Pébay

The paper uses iPSC-derived RPE cells to compare molecular differences between AMD with and without reticular pseudodrusen, identifying distinct pathways and genetic influences.

Genome Medicine · May 9, 2026Peer-reviewedGenetics

Village in a dish: a model system for population-scale hiPSC studies

Drew R. Neavin, Angela M. Steinmann, Nona Farbehi, Han Sheng Chiu, Maciej Daniszewski, Himanshi Arora, Yasmin Bermudez, Cátia Moutinho, Chia‐Ling Chan, Monique Bax, Mubarika Tyebally, Vikkitharan Gnanasambandapillai, Chuan En Lam, Uyen T. T. Nguyen, Damián Hernández, , Joseph E. Powell

The paper demonstrates that village cultures of hiPSCs maintain consistent transcriptional profiles across uni- and village-cultured samples, enabling population-scale studies.

Nature Communications · Jun 9, 2023Peer-reviewedGenomics

Transcriptomic and proteomic retinal pigment epithelium signatures of age-related macular degeneration.

Anne Senabouth, Maciej Daniszewski, Grace E. Lidgerwood, Helena Hai Liang, Damián Hernández, Mehdi Mirzaei, Stacey N. Keenan, Ran Zhang, Xikun Han, Drew R. Neavin, Louise A. Rooney, Maria Isabel G. Lopez Sanchez, Lerna M. Gulluyan, João A. Paulo, Linda Clarke, , Alice Pébay

This study identifies genetic and molecular differences in RPE cells from geographic atrophy patients compared to controls using transcriptomic and proteomic analyses.

Nature Communications · Jul 26, 2022Peer-reviewedNeuroscience

Retinal ganglion cell-specific genetic regulation in primary open angle glaucoma

Maciej Daniszewski, Anne Senabouth, Helena Hai Liang, Xikun Han, Grace E. Lidgerwood, Damián Hernández, Priyadharshini Sivakumaran, Jordan Elli Clarke, Shiang Yong Lim, Jarmon G. Lees, Louise A. Rooney, Lerna M. Gulluyan, Emmanuelle Souzeau, Stuart L. Graham, Chia‐Ling Chan, , Alex William Hewitt

This study uses iPSC-derived retinal organoids to identify retinal ganglion cell-specific expression quantitative trait loci associated with primary open-angle glaucoma.

Cell Genomics · Jun 1, 2022Peer-reviewedGenetics

Single cell eQTL analysis identifies cell type-specific genetic control of gene expression in fibroblasts and reprogrammed induced pluripotent stem cells

Drew R. Neavin, Quan Hoang Nguyen, Maciej Daniszewski, Helena Hai Liang, Han Sheng Chiu, Anne Senabouth, Samuel W. Lukowski, Duncan E. Crombie, Grace E. Lidgerwood, Damián Hernández, James Clement Vickers, Anthony L. Cook, Nathan J. Palpant, Alice Pébay, Alex William Hewitt, Joseph E. Powell

The paper identifies cell type-specific genetic control of gene expression in fibroblasts and iPSCs using single-cell RNA sequencing and eQTL mapping.

Genome Biology · Dec 1, 2021Peer-reviewedGenomics