Author

Yuchen Pan

The University of Texas MD Anderson Cancer CenterORCID 0000-0002-1780-764XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Bioinformatics· 1 Immunology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:benchmarking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:mouse· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Ashley M. GuerreroiD· 1 shared Black McCourt· 1 shared Chenggui Xu· 1 shared Eduardo G. Gonzalez SantiagoiD· 1 shared Fang ZhouiD· 1 shared George C. TsengiD· 1 shared Hung‐Ching ChangiD· 1 shared Jessica M. ToothakeriD· 1 shared

Activity by Year

2024-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperImmunology

Ashley M. GuerreroORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Comprehensive evaluation and practical guideline of gating methods for high-dimensional cytometry data: manual gating, unsupervised clustering, and auto-gating

Peng Liu, Yuchen Pan, Hung‐Ching Chang, Wenjia Wang, Yusi Fang, Xiangning Xue, Jian Zou, Jessica M. Toothaker, Oluwabunmi O. Olaloye, Eduardo G. Gonzalez Santiago, Black McCourt, Vanessa Mitsialis, Pietro Presicce, Suhas G. Kallapur, Scott B. Snapper, , Silvia Liu

This study evaluates manual gating, unsupervised clustering, and auto-gating methods for high-dimensional cytometry data using six datasets and provides practical guidelines for selecting appropriate methods.

Briefings in Bioinformatics · Nov 22, 2024Peer-reviewedBioinformatics

LRRK2 G2019S mutation suppresses differentiation of Th9 and Treg cells via JAK/STAT3

Ningbo Zheng, Roshni Jaffery, Ashley M. Guerrero, Jiakai Hou, Yuchen Pan, Fang Zhou, Si Chen, Chenggui Xu, Nicholas A. Egan, Ritu Bohat, Ken Chen, Michael A. Schwarzschild, Xiqun Chen, Weiyi Peng

This study shows that the LRRK2 G2019S mutation impairs Th9 and Treg cell differentiation while enhancing Th2 differentiation through JAK/STAT3 signaling in T cells.

bioRxiv · Feb 28, 2024 · PreprintImmunology