Author

Philip J. Y. Leung

University of WashingtonORCID 0000-0002-1801-8968Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioengineering· 1

Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:protein design· 1 Assay:protein structure· 1 Approach:transformer / foundation model· 1

Frequent Co-Authors

Andrew J. BorstiD· 1 shared Basile I. M. WickyiD· 1 shared Benedikt SingeriD· 1 shared Buwei HuangiD· 1 shared Cameron CriswelliD· 1 shared Chang C. LiuiD· 1 shared Connor WeidleiD· 1 shared David A. BakeriD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperBioengineering

Andrew J. BorstORCID

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Author profile →

1 paper

Recent·Most cited

Atomically accurate de novo design of antibodies with RFdiffusion

Nathaniel R. Bennett, Joseph L. Watson, Robert J. Ragotte, Andrew J. Borst, DéJenaé L. See, Connor Weidle, Riti Biswas, Yutong Yu, Ellen L. Shrock, Russell Ault, Philip J. Y. Leung, Buwei Huang, Inna Goreshnik, John Tam, Kenneth D. Carr, , David A. Baker

This paper designs antibodies de novo with atomic precision using RFdiffusion and yeast display, validated by cryo-EM and biophysical methods.

Nature · Nov 5, 2025Peer-reviewedBioengineering