Author

Yutong Yu

University of California, IrvineORCID 0009-0000-4656-9700Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioengineering· 1 Synthetic Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:protein design· 2 Research Focus:benchmarking· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Assay:protein structure· 1 Approach:transformer / foundation model· 1 Organism:yeast· 1

Frequent Co-Authors

Chang C. LiuiD· 2 shared Alexander Pisera· 1 shared Andrew J. BorstiD· 1 shared Basile I. M. WickyiD· 1 shared Benedikt SingeriD· 1 shared Buwei HuangiD· 1 shared Cameron CriswelliD· 1 shared Connor WeidleiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersBioengineering

Chang C. LiuORCID

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2 papers

Recent·Most cited

BioengineeringNaturePeer-reviewedNov 5, 2025

Atomically accurate de novo design of antibodies with RFdiffusion

Nathaniel R. Bennett, Joseph L. Watson, Robert J. Ragotte…·David A. Baker

This paper designs antibodies de novo with atomic precision using RFdiffusion and yeast display, validated by cryo-EM and biophysical methods.

381 citationstop 1%

protein structuredeep learning

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Synthetic BiologyACS Synthetic BiologyPeer-reviewedMar 24, 2025

Ultra-Efficient Integration of Gene Libraries onto Yeast Cytosolic Plasmids

Alexander Pisera, Yutong Yu, Rory L. Williams, Chang C. Liu

The paper introduces a method to efficiently integrate gene libraries onto yeast cytosolic plasmids using integrases, enhancing the versatility of OrthoRep for protein engineering.

4 citations

yeastexperimental assay

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