Cécile Leduc

This study shows vimentin promotes actin elongation by stabilizing ATP-actin subunits at the barbed end, and it enhances actin nucleation through a direct interaction with ATP-actin monomers.

The paper introduces a drag flow method to study protein-protein interactions, showing that low forces detach tropomyosin clusters from actin filaments, with detachment rates depending on isoform and force magnitude.

This study investigates the mechanism of vimentin filament disassembly, revealing continuous self-repair and subunit exchange dynamics that prevent fragmentation.