Author

Michael J. Rogers

Garvan Institute of Medical ResearchORCID 0000-0002-1818-9249Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1

Frequent Co-Authors

Agnieszka K. BronowskaiD· 1 shared Amelia StennettiD· 1 shared Bernardo S. FrankliniD· 1 shared Chloe M. McKeeiD· 1 shared Damien BerthelootiD· 1 shared Emma C. McKayiD· 1 shared Junya Zhang· 1 shared Marcia A. MunoziD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperImmunology

Agnieszka K. BronowskaORCID

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1 paper

Recent·Most cited

NLRP3 is a thermosensor that is negatively regulated by high temperature

Wei Wang, Damien Bertheloot, Junya Zhang, Marcia A. Munoz, Shangze Xu, Amelia Stennett, Chloe M. McKee, Ryan Knight, Emma C. McKay, Bernardo S. Franklin, Michael J. Rogers, Agnieszka K. Bronowska, Rebecca C. Coll

This study shows high temperatures inhibit NLRP3 inflammasome activation, identifying NLRP3 as a thermosensor and revealing a temperature-sensitive conformational change in its C-terminal domain.

bioRxiv · Sep 29, 2025 · PreprintImmunology