Developmental BiologybioRxivPreprint
Context-dependent requirement of H3K9 methyltransferase activity during cellular reprogramming to iPSCs
Simon E. Vidal, Alexander Polyzos, Jorge Morales-Valencia…·Matthias Stadtfeld
This study shows that reducing EHMT1/2 activity during reprogramming with ascorbic acid impairs iPSC formation and viability, highlighting the role of H3K9 methylation in reprogramming efficiency.
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