Molecular BiologyThe EMBO JournalPeer-reviewed
A rare human centenarian variant of SIRT6 enhances genome stability and interaction with Lamin A
Matthew A. Simon, Jiping Yang, Jonathan Gigas…·Vera A. Gorbunova
The paper identifies a SIRT6 variant enriched in centenarians that improves genome stability through enhanced mADPr activity and interaction with Lamin A.
73 citationstop 1%