Vladimir Ljubicic

Arginine methyltransferase signalling is hyperactive in conditions of neuromuscular junction instability and muscle atrophy

This study shows that CARM1 activity increases in neuromuscular junction instability and muscle atrophy in mice and humans, correlating with NMJ dysfunction and muscle health decline.

Acute AMPK activation does not adequately stimulate insulin signaling in skeletal muscle models of Myotonic Dystrophy Type 1

This study shows that acute AMPK activation fails to improve insulin signaling in DM1 mouse and human models, indicating impaired insulin resistance mechanisms.