Author

James R. Cook

University of FreiburgORCID 0000-0002-1905-4928Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

Catherine B. LawrenceiD· 1 shared David BroughiD· 1 shared J. P. GreeniD· 1 shared Kevin N. CouperiD· 1 shared Sara GagoiD· 1 shared Stuart McRae AllaniD· 1 shared Tara A. GleesoniD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 21 mutual co-author links

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1 shared paperImmunology

Catherine B. LawrenceORCID

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1 paper

Recent·Most cited

ImmunologyThe Journal of Cell BiologyPeer-reviewedMar 13, 2026

Cell volume tunes macrophage innate inflammatory responses through promoting type I interferon signalling.

James R. Cook, Tara A. Gleeson, Sara Gago…·J. P. Green

This study shows that cell volume changes in macrophages enhance type I interferon signaling and inflammation through a DNA- and STING-dependent mechanism.

2 citations

mousebulk RNA-seq