Author

Tara A. Gleeson

Manchester Academic Health Science CentreORCID 0000-0001-9850-1134Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Immunology· 2

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Approach:statistical model· 1

Frequent Co-Authors

Catherine B. LawrenceiD· 2 shared David BroughiD· 2 shared J. P. GreeniD· 2 shared Stuart McRae AllaniD· 2 shared Christina KaiseriD· 1 shared James R. CookiD· 1 shared Kevin N. CouperiD· 1 shared Sara GagoiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 25 mutual co-author links

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2 shared papersImmunology

Catherine B. LawrenceORCID

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2 papers

Recent·Most cited

ImmunologyThe Journal of Cell BiologyPeer-reviewedMar 13, 2026

Cell volume tunes macrophage innate inflammatory responses through promoting type I interferon signalling.

James R. Cook, Tara A. Gleeson, Sara Gago…·J. P. Green

This study shows that cell volume changes in macrophages enhance type I interferon signaling and inflammation through a DNA- and STING-dependent mechanism.

2 citations

mousebulk RNA-seq

𝕏 PostBluesky

ImmunologyDisease Models & MechanismsPeer-reviewedMay 22, 2024

The NLRP3 inflammasome is essential for IL-18 production in a murine model of macrophage activation syndrome.

Tara A. Gleeson, Christina Kaiser, Catherine B. Lawrence…·J. P. Green

This study shows the NLRP3 inflammasome is crucial for IL-18 production in a murine model of MAS but not for other disease features.

20 citations

mousebulk RNA-seq

𝕏 PostBluesky