Author

Xin Chen

Shanghai Institute of Nutrition and HealthORCID 0000-0002-1920-8835Unclaimed ORCID profile · follow to get notified of new preprints

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Xin Chen20 papers · Campbell University

Biology Disciplines

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Cell Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Approach:experimental assay· 1 Research Focus:metabolism & bioenergetics· 1 Organism:mouse· 1

Frequent Co-Authors

Bo ZhongiD· 1 shared Dandan LiniD· 1 shared Fuling ZhouiD· 1 shared Hao-Yu Duan· 1 shared Huiyong YiniD· 1 shared Jia YuiD· 1 shared Peng WangiD· 1 shared Shengdan ZhangiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperCell Biology

Bo ZhongORCID

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1 paper

Recent·Most cited

Tumor cell-specific loss of GPX4 reprograms triacylglycerol metabolism to escape ferroptosis and impair antitumor immunity in NSCLC

Peng Wang, Shengdan Zhang, Xin Chen, Xu-Dong Yang, Shi Huang, Huiyong Yin, Hao-Yu Duan, Fuling Zhou, Jia Yu, Bo Zhong, Dandan Lin

This study shows that GPX4 loss in tumor cells promotes NSCLC by reprogramming lipid metabolism and suppressing antitumor immunity through ferroptosis evasion and immunoinhibitory TME.

Protein & Cell · Nov 19, 2025Peer-reviewedCell Biology