Christophe Audouard

The paper investigates the role of Snord116 and Snord115 genes in Prader-Willi syndrome using knockout mice and comparative genomics, finding their impact on growth, metabolism, and gene regulation.

This study shows that acute methionine restriction during mouse neocortex development severely reduces growth and neuronal production, but this effect is reversible with dietary recovery.

This study shows that reducing DHFR activity in neural progenitors accelerates indirect neurogenesis and alters neuronal composition in human and mouse neocortex.

This study shows that CDC25B regulates G2 phase duration, affecting the balance between direct and indirect neurogenesis in the developing mouse neocortex.

The paper shows apical progenitors in the developing neocortex have heterogeneous apical surface areas, and Ephrin B1 regulates this size without affecting proliferation or differentiation.

This study shows ephrin-B2 regulates the timing and number of neuronal production in the developing neocortex through juxtacrine signaling on neural progenitors.

The paper shows that Eph-B signaling affects 1C metabolism in neural stem cells, altering H3K4 methylation and promoting differentiation.

This study shows Eph:ephrin signaling maintains progenitor identities in the ventral spinal cord by regulating transcription factor expression.