David Ohayon

Neocortical astrocyte diversity stems from distinct developmental origins

The paper identifies distinct developmental origins of neocortical astrocytes using multimodal techniques and reveals their unique lineage and developmental trajectory.

Acute dietary methionine restriction highlights sensitivity of neocortex development to metabolic variations

This study shows that acute methionine restriction during mouse neocortex development severely reduces growth and neuronal production, but this effect is reversible with dietary recovery.

DHFR metabolic activity controls neurogenic transitions in the developing Human and mouse neocortex

This study shows that reducing DHFR activity in neural progenitors accelerates indirect neurogenesis and alters neuronal composition in human and mouse neocortex.

Transcriptome profiling of the Olig2-expressing astrocyte subtype reveals their unique molecular signature

The paper identifies a unique molecular signature of Olig2-expressing astrocytes through transcriptome profiling and differential gene expression analysis.

Sulf2a controls Shh-dependent neural fate specification in the developing spinal cord

This study shows that Sulf2a regulates Shh-dependent neural fate specification in zebrafish spinal cord development by modulating Shh signaling and cell type differentiation.

Identification of a Sulf2-dependant astrocyte subtype that stands out through the expression of Olig2 in the ventral spinal cord

The paper identifies an Olig2-expressing astrocyte precursor subtype in the ventral spinal cord that depends on Sulf2 for its generation.