This paper introduces an automated framework for naming cells in ascidian embryos, revealing consistent and variable features of embryogenesis across species and conditions.

bioRxiv · Oct 13, 2025 · PreprintDevelopmental Biology

Unveiling mechanical interactions between cell division and extracellular matrix in human colonic epithelium organoids: A 4D study using DVC

Laurent Magne, Thomas Pottier, Déborah Michel, Julien Laussu, Delphine Bonnet, Laurent Alric, Stéphane Segonds, Gaëlle Recher, Florian Bugarin, Audrey Ferrand

The paper studies how cell division affects the extracellular matrix in human colonic epithelium organoids using 4D imaging and Digital Volume Correlation.

Scientific Reports · Jul 1, 2025Peer-reviewedCell Biology

Contact-dependent cell communications drive morphological invariance during ascidian embryogenesis

Léo Guignard, Ulla-Maj Fiúza, Bruno Leggio, Julien Laussu, Emmanuel Faure, Gaël Michelin, Kilian Biasuz, Lars Hufnagel, Grégoire Malandain, Christophe Godin, Patrick Lemaire

The paper investigates how contact-dependent cell communications maintain morphological invariance during ascidian embryogenesis despite genomic divergence.

Science · Jul 9, 2020Peer-reviewedDevelopmental Biology

Eph/ephrin signaling controls progenitor identities in the ventral spinal cord

Julien Laussu, Christophe Audouard, Anthony Kischel, Poincyane Assis-Nascimento, Nathalie Escalas, Daniel J. Liebl, Cathy Soula, Alice Davy

This study shows Eph:ephrin signaling maintains progenitor identities in the ventral spinal cord by regulating transcription factor expression.

Neural Development · Jun 8, 2017Peer-reviewedDevelopmental Biology