Author

Prachi Gupta

University of Massachusetts AmherstORCID 0000-0002-1928-095XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioengineering· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Assay:protein structure· 1

Frequent Co-Authors

Badal SinghiD· 1 shared Ranit DuttaiD· 1 shared S. ThayumanavaniD· 1 shared Yasin Alp· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

4 top collaborators · 6 mutual co-author links

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1 shared paperBioengineering

Badal SinghORCID

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1 paper

Recent·Most cited

BioengineeringbioRxivPreprintMay 6, 2025

Multivalent Ligand-Protein Interactions Using Polymeric Lysosome-Targeting Chimeras (PolyTACs) Leads to Lysosome-Targeting Receptor-Independent Degradation of Transmembrane Proteins

Ranit Dutta, Yasin Alp, Prachi Gupta…·S. Thayumanavan

The paper demonstrates that multivalent ligand-protein interactions using PolyTACs can degrade transmembrane proteins without lysosome-targeting receptors.

1 citation

protein structureexperimental assay

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