Cobi J. Heijnen

The paper shows that B cell-derived IgG in DRG meninges forms tertiary lymphoid structures (TLSs) that drive neuropathic pain after peripheral nerve injury, and disrupting TLSs prevents pain.

This study shows that B cell-derived autoreactive IgG and FcγR upregulation drive mechanical allodynia after nerve constriction or crush injury, but not after nerve transection.

This study identifies IL-10's role in upregulating delta opioid receptor to prevent pain relapse during remission.

This study shows astrocytes transfer healthy mitochondria to cisplatin-damaged neurons, improving their survival, mitochondrial function, and calcium dynamics.

This study identifies PI16 as a non-neuronal factor produced by fibroblasts that promotes neuropathic pain by modulating endothelial barrier function and leukocyte infiltration.