Bertrand Bénazéraf

This study develops a mathematical model to simulate how differential proliferation and mechanical interactions influence embryonic axial extension across multiple tissues.

The paper shows that variations in Sox2-to-Bra protein ratios in posterior progenitors influence their motility and fate, guiding their contribution to neural or mesodermal tissues.

The paper shows that SMAD3-driven cell intercalation is essential for forming a single central lumen during secondary neural tube development in chicken embryos.

The paper shows that mechanical interactions coordinate the elongation of axial and paraxial tissues in avian embryos through a feedback loop involving cell motility and compression.

The paper quantifies tissue behavior during amniote embryo axis elongation using 4D imaging and analysis techniques, revealing coordinated tissue movements and the central role of the PSM in elongation.