Susana Usieto

Rootletin Fiber Dynamics Integrate Cytoskeletal Programs to Shape Neuroepithelial Architecture

This study reveals Rootletin's dynamic role in neuroepithelial cell morphogenesis and shows its aberrant interaction with Zika virus NS5 protein, linking infection to premature delamination.

Neural crest-related NXPH1/α-NRXN signaling opposes neuroblastoma malignancy by inhibiting metastasis

The paper identifies a transcriptional signature distinguishing low- and high-risk neuroblastomas and shows that NXPH1/-NRXN signaling inhibits metastasis while promoting tumor growth.

Cell intercalation driven by SMAD3 underlies secondary neural tube formation

The paper shows that SMAD3-driven cell intercalation is essential for forming a single central lumen during secondary neural tube development in chicken embryos.

A SMAD1/5-YAP signaling module drives radial glia self-amplification and growth of the developing cerebral cortex

This study identifies a SMAD1/5-YAP signaling module that regulates radial glia self-amplification and cortical growth during development.

E proteins differentially co-operate with proneural bHLH transcription factors to sharpen neurogenesis

The paper shows E proteins differentially cooperate with proneural bHLH transcription factors to sharpen neurogenesis by acting on specific DNA motifs.