Fengzhu Xiong

This study reveals that symbiont spatial organisation in cnidarian host tissues is dynamically regulated through mechanical constraints and environmental changes.

The paper quantifies Shh response dynamics in zebrafish neural progenitors and finds significant heterogeneity between Shh response and fate choice.

TiFM2.0 improves mechanical measurement and actuation in live embryos with a double-probe system, demonstrating applications in chicken and zebrafish embryos.

The paper shows that tissue spreading during epiboly in chicken embryos reorganizes the extracellular matrix to establish blastoderm architecture and polarity.

The paper develops a model to explain the development of labyrinthine maxilloturbinate structures in seals, showing it replicates key structural features observed in tomographic data.

The paper shows that cell density in the posterior presomitic mesoderm modulates body axis elongation speed through a negative feedback loop, coupling tissue mechanics and FGF activity.

The paper describes a method to modulate lumen pressure in chicken embryos using a pressure sensor and water column.

This paper introduces TiFM, a technique for measuring and applying forces to small tissues in early chicken embryos, showing it can capture stress dynamics and alter morphogenetic processes.

This study shows that reducing tension in the avian vitelline membrane facilitates proper body axis formation by allowing controlled morphogenesis and preventing developmental defects.

The paper shows that mechanical interactions coordinate the elongation of axial and paraxial tissues in avian embryos through a feedback loop involving cell motility and compression.

The paper shows that aerobic glycolysis increases intracellular pH in tail bud cells, promoting β-catenin acetylation and Wnt signaling, which drives mesodermal fate over neural fate.

The paper shows that Warburg-like metabolism in the posterior region of embryos coordinates FGF and Wnt signaling to promote embryonic axis elongation.