Author

Martin Lothar Metzelder

Medical University of ViennaORCID 0000-0002-1951-7582Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell-cell communication· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Branka Radic-SarikasiD· 2 shared Florian HalbritteriD· 2 shared Heinrich KovariD· 2 shared Helena SorgeriD· 2 shared Martha Magdalena ZylkaiD· 2 shared Aleksandr OvsianikoviD· 1 shared Antonin MarchaisiD· 1 shared Bernadette Liegl‐AtzwangeriD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersCancer Biology

Branka Radic-SarikasORCID

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3 papers

Recent·Most cited

Cancer BiologybioRxivPreprintJun 8, 2026

A human lung organoid co-culture model of early bone sarcoma metastasis reveals contact-dependent epithelial remodeling at the metastatic interface

Martha Magdalena Zylka, Tümay Capraz, Gaël Moquin‐Beaudry…·Branka Radic-Sarikas

This paper introduces a 3D co-culture model of bone sarcoma metastasis in the lung and identifies a contact-dependent epithelial remodeling response with potential therapeutic targets.

DOI 10.64898/2026.06.03.729838

humanspatial transcriptomics

𝕏 PostBluesky

Cancer BiologyMolecular Therapy OncologyPeer-reviewedMay 9, 2026

Mevalonate pathway activation in Ewing sarcoma reveals a 3D-specific synergy between statins and BCL-xL inhibition

Branka Radic-Sarikas, Marica Marković, Martha Magdalena Zylka…·Heinrich Kovar

The paper develops a 3D culture platform for Ewing sarcoma and identifies a synergy between statins and BCL-xL inhibitors targeting the mevalonate pathway.

DOI 10.1016/j.omton.2026.201229

humanbulk RNA-seq

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Cancer BiologybioRxivPreprintMar 3, 2025

Targeting the hyperactive STAT3/5 pathway in cutaneous T-cell lymphoma with the multi-kinase nuclear transporter inhibitor IQDMA

Saptaswa Dey, Helena Sorger, Michaela Schlederer…·Peter Wolf

This study evaluates IQDMA, a multi-kinase inhibitor, as a targeted therapy for cutaneous T-cell lymphoma, showing significant tumor volume reduction and STAT3/5 pathway inhibition compared to PUVA.

DOI 10.1101/2025.03.03.641168

mouseexperimental assay

𝕏 PostBluesky