Gaël Moquin‐Beaudry

This paper introduces a 3D co-culture model of bone sarcoma metastasis in the lung and identifies a contact-dependent epithelial remodeling response with potential therapeutic targets.

The paper shows senescent human fibroblasts increase FasL expression, leading to T and NK cell apoptosis and impaired tumor immune response in humanized models.

This paper describes engineered liver tissue that reverses acute liver failure in mice without immunosuppression, demonstrating potential for clinical translation.

This study uses single-cell sequencing to analyze peripheral immune cell changes in Parkinson's disease patients, identifying key immune signatures and potential biomarkers.

This study shows that two ketogenic diets improve cognition and metabolic health in Alzheimer's disease mouse models, with distinct effects on peripheral metabolism.

CellsFromSpace is a reference-free tool for deconvolving and annotating spatial transcriptomic data, outperforming existing methods in accuracy and speed across multiple technologies.