Author

Derek C. Radisky

Mayo Clinic in FloridaORCID 0000-0002-1962-8784Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:gene regulatory network inference· 1 Assay:proteomics· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Amy C. DegnimiD· 2 shared Anguraj SadanandamiD· 2 shared Chitra Priya EmperumaliD· 2 shared David J. H. F. KnappiD· 2 shared Judy Caroline BougheyiD· 2 shared Mark E. ShermaniD· 2 shared Megan L. RittingiD· 2 shared Nagarajan KannaniD· 2 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersCancer Biology

Amy C. DegnimORCID

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2 papers

Recent·Most cited

The Human Male Mammary Gland has Similar Epithelial Populations to Female but Distinct Composition and Transcriptional Properties

Myriam Iliana Ibanez-Rios, Syed Mohammed Musheer Aalam, Megan L. Ritting, Ashlyn Jore, Keyur Chaludia, Chitra Priya Emperumal, James W. Jakub, Sarah A. McLaughlin, Amy C. Degnim, Judy Caroline Boughey, Fergus J. Couch, Siddhartha Yadav, Anguraj Sadanandam, Mark E. Sherman, Derek C. Radisky, , Nagarajan Kannan

This paper presents a single-cell RNA sequencing atlas of the adult human male breast, revealing distinct transcriptional properties and composition compared to female breast tissue.

bioRxiv · Mar 31, 2026 · PreprintCancer Biology

Receptor Tyrosine Kinase Profiling Identifies Chronic Constitutive Floodgate Oxidative Signaling in Glutathione-Independent Human Mammary Luminal Progenitor Cells

Syed Mohammed Musheer Aalam, Megan L. Ritting, Hari PS, Geng‐Xian Shi, Kingsley Shih, Yifei Dong, Guruprasad Kalthur, Miao Cao, Yifan Yu, David J. H. F. Knapp, Peter D. Eirew, Davide Pellacani, Chitra Priya Emperumal, Hequn Wang, Jeffrey R. Janus, , Nagarajan Kannan

This study identifies cKIT as a key mediator of oxidative signaling in human mammary luminal progenitor cells and links its activation to poor outcomes in basal-like breast cancers.

bioRxiv · Jul 15, 2025 · PreprintCancer Biology