Murali Dharan Bashyam

ARID2 loss destabilizes PBAF and drives colorectal cancer

This study shows ARID2 loss destabilizes the PBAF complex, leading to CRC progression through disrupted chromatin remodeling and pathway perturbations.

E3 ubiquitin ligase WWP2 regulates stability and tumor suppressive properties of the chromatin remodeler ARID1B

This study identifies WWP2 as an E3 ubiquitin ligase that regulates ARID1B protein stability and tumor suppressive function through ubiquitination.

An Atlas of Indian Genetic Diversity

The paper presents a comprehensive genomic atlas of Indian populations, identifying novel variants and highlighting genetic diversity and pharmacogenomic implications.

Evaluation of the gene fusion landscape in early onset sporadic rectal cancer reveals association with chromatin architecture and genome stability

The paper evaluates gene fusions in early-onset sporadic rectal cancer, linking them to chromatin architecture and genome stability.

Mutational landscape and dominant lineages in the SARS-CoV-2 infections in the state of Telangana, India

The paper analyzes the mutational landscape of SARS-CoV-2 infections in Telangana, India, to identify dominant viral clades and their genomic variants.

PAN-INDIA 1000 SARS-CoV-2 RNA Genome Sequencing Reveals Important Insights into the Outbreak

The paper sequences 1000 SARS-CoV-2 genomes from India, revealing multiple circulating lineages, predominant A2a haplotype with D614G mutation, and geographic mutation clustering.