Author

Paulene Sapao

Virginia Commonwealth UniversityORCID 0000-0002-1986-6491Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:human· 1 Organism:mouse· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

John VargaiD· 2 shared Le My Tu NguyeniD· 2 shared Maria Eugenia TevesiD· 2 shared Adam KlumppiD· 1 shared Audrey D. LafrenayeiD· 1 shared Carlos Córdova‐FletesiD· 1 shared Carlos E. CórdovaiD· 1 shared Catherine Vasquez-Hernandez· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersCell Biology

John VargaORCID

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2 papers

Recent·Most cited

Imbalance of Ciliary Programs Drives Fibroblast Differentiation and Fibrotic Signaling in Systemic Sclerosis

Le My Tu Nguyen, Carlos E. Córdova, Paulene Sapao, Catherine Vasquez-Hernandez, Adam Klumpp, Le Phuc Diem Nguyen, Poulami Dey, Johann Eli Gudjonsson, Rebecca L. Ross, Francesco Del Galdo, Natalia A. Riobo‐Del Galdo, Priyanka Verma, John Varga, Maria Eugenia Teves

This study identifies ciliary program imbalance as a driver of fibroblast-to-myofibroblast reprogramming in systemic sclerosis, suggesting ciliotherapy as a potential treatment.

bioRxiv · Feb 25, 2026 · PreprintCell Biology

Regulation of Female Reproductive Aging by the Spag17 Gene

Valerie Ericsson, Madisyn Elam, Paulene Sapao, Le My Tu Nguyen, Mary Ellen Gill, Saikeerthana Chodavarapu, Carlos Córdova‐Fletes, Audrey D. Lafrenaye, Sonia S. Hassan, Mala Mahendroo, Li Chen, Mathieu M. Petitjean, Jerome F. Strauss, John Varga, Francesca E. Duncan, Maria Eugenia Teves

This study identifies Spag17 as a key modulator of female reproductive aging, showing its role in maintaining fertility and preventing age-related complications.

bioRxiv · Mar 1, 2025 · PreprintCell Biology