Author

Jose D. Vargas

National Cancer InstituteORCID 0000-0002-2005-567XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetic & Genomic Medicine· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Organism:human· 2 Approach:statistical model· 2 Assay:whole-genome sequencing· 2 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Abdul Rouf BandayiD· 1 shared Adam J. GehringiD· 1 shared Alicia K. SmithiD· 1 shared Amadou GayeiD· 1 shared Amy A HutchinsoniD· 1 shared Andrea N. Burnett‐HartmaniD· 1 shared Anurag VermaiD· 1 shared Benedito Antônio Lopes da FonsecaiD· 1 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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1 shared paperGenetic & Genomic Medicine

Abdul Rouf BandayORCID

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2 papers

Recent·Most cited

Regulatory Roles of Long Non-Coding RNAs in Arterial Stiffness and Hypertension: Insights from Two African American Studies

Jose D. Vargas, Malak Abbas, Gabriel A. Goodney, Amadou Gaye

This study identifies lncRNAs and mRNAs associated with arterial stiffness and hypertension in African American populations using transcriptome data from two cohorts.

bioRxiv · Aug 11, 2024 · PreprintGenomics

Genetic regulation of OAS1 nonsense-mediated decay underlies association with risk of severe COVID-19

Abdul Rouf Banday, Megan Lynn Stanifer, Oscar Flórez-Vargas, Olusegun O. Onabajo, Brenen W. Papenberg, Muhammad Atif Zahoor, Lisa J. Mirabello, Timothy J. Ring, Chia-Han Lee, Paul S. Albert, Evangelos Andreakos, Evgeny Arons, Gregory S. Barsh, Leslie G. Biesecker, David L. Boyle, , Ludmila Prokunina‐Olsson

The paper identifies a Neandertal introgressed haplotype in the OAS1 gene associated with increased risk of severe COVID-19 and shows it impairs SARS-CoV-2 clearance through genetic regulation of OAS1 expression.

Nature Genetics · Jul 14, 2022Peer-reviewedGenetic & Genomic Medicine