Author

Davide Tavella

University of Massachusetts Chan Medical SchoolORCID 0000-0002-2030-2087Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:C. elegans· 1

Frequent Co-Authors

Alicia Newton· 1 shared Ayşegül ÖzeniD· 1 shared Celia A. SchifferiD· 1 shared Christos J. PetropoulosiD· 1 shared Cihan AydıniD· 1 shared Francesca MassiiD· 1 shared Katianna R. Antkowiak· 1 shared Keith P. RomanoiD· 1 shared

Activity by Year

2018-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperMolecular Biology

Alicia Newton

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2 papers

Recent·Most cited

GeneticsG3 Genes Genomes GeneticsPeer-reviewedNov 13, 2023

A nematode model to evaluate microdeletion phenotype expression

Katianna R. Antkowiak, Peren Coskun, Sharon T. Noronha…·Sean P. Ryder

This paper describes a microdeletion allele in C. elegans generated via CRISPR/Cas9, which removes 32 genes and causes complex developmental phenotypes.

1 citation

C. elegansexperimental assay

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Molecular BiologybioRxivPreprintDec 16, 2018

Resistance from Afar: Distal Mutation V36M Allosterically Modulates the Active Site to Accentuate Drug Resistance in HCV NS3/4A Protease

Ayşegül Özen, Kuan-Hung Lin, Keith P. Romano…·Celia A. Schiffer

This study investigates how the distal mutation V36M confers drug resistance in HCV NS3/4A protease through allosteric modulation of the active site, in the context of R155K.

1 citation

experimental assay

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