Author

Mollie K. Huber

University of Florida HealthORCID 0000-0002-2031-0116Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1 Assay:proteomics· 1

Frequent Co-Authors

Alexandra E. CuaycaliD· 2 shared Dylan SmurlickiD· 2 shared Edward A. PhelpsiD· 2 shared Mark A. AtkinsoniD· 2 shared Adrienne E. WideneriD· 1 shared Ana Laura ChiodettiiD· 1 shared Andrew M. LaddiD· 1 shared Clayton E. MathewsiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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2 shared papersBioengineering

Alexandra E. CuaycalORCID

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2 papers

Recent·Most cited

BioengineeringbioRxivPreprintOct 21, 2025

Inhibition of cell-mediated immunity in type 1 diabetes by beta cell-targeted PD-1 agonists in pancreas tissue slices

Matthew W. Becker, Matthew E. Brown, Katherine Wiseman…·Edward A. Phelps

This study shows that ImmTAAI, a beta cell-targeted PD-1 agonist, inhibits T cell activity in human type 1 diabetes by increasing T cell motility and reducing cytokine secretion.

DOI 10.1101/2025.10.21.683528

humanproteomics

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PhysiologyCell ReportsPeer-reviewedAug 27, 2025

Beta cell dysfunction occurs independently of insulitis in type 1 diabetes pathogenesis

Mollie K. Huber, Adrienne E. Widener, Alexandra E. Cuaycal…·Edward A. Phelps

This study shows that beta cell dysfunction occurs in type 1 diabetes independently of T cell infiltration, using human pancreas tissue slices from recently diagnosed patients.

35 citationstop 1%

humanbulk RNA-seq

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