Author
University of GeorgiaORCID 0000-0002-2041-6295Unclaimed ORCID profile · follow to get notified of new preprints
6 papers
Recent·Most cited
Baihetiya Baierna, Silvia N J Moreno
This study identifies a respiratory microdomain in Toxoplasma gondii that links ubiquinone biosynthesis to succinate dehydrogenase, revealing a unique mitochondrial organization lacking complex I.
Melissa A. Sleda, Khaly Diagne, Victoria M. Clifton…·Silvia N.J. Moreno
This study evaluates two 4(1H)-quinolone compounds for their efficacy against both acute and chronic Toxoplasma gondii infection, showing potent activity against tachyzoites and bradyzoites.
Baihetiya Baierna, Taufiq Rahman, Scott Latimer…·Silvia N.J. Moreno
The paper identifies a unique bi-functional monooxygenase in Toxoplasma gondii essential for ubiquinone biosynthesis and presents inhibitors targeting this enzyme.
Katherine E Moen, Silvia N.J. Moreno
This study identifies TgPDIA3's role in coordinating ER redox homeostasis and calcium regulation to support Toxoplasma gondii lytic cycle progression.
Zhu‐Hong Li, Beejan Asady, Le Chang…·Silvia N.J. Moreno
This study identifies the role of SERCA-Ca2+-ATPase in maintaining Ca2+ homeostasis in Toxoplasma gondii by redistributing Ca2+ from the ER to other organelles.
Davinder Singh, Melissa A. Sleda, Akanksha M. Pandey…·Eric Oldfield
The paper tests carbazole, aminoguanidine, and diamine anti-infectives against Toxoplasma gondii, finding low IC50 values and protonophore uncoupling activity.