ImmunologyFrontiers in ImmunologyPeer-reviewed
Lack of phosphatidylinositol 3-kinase VPS34 in regulatory T cells leads to a fatal lymphoproliferative disorder without affecting their development
Christina J. F. Courrèges, Elizabeth C. M. Davenport, Benoît Bilanges…·Klaus Okkenhaug
This study shows that VPS34 deficiency in regulatory T cells causes a fatal lymphoproliferative disorder by impairing metabolic and functional processes, despite normal development and in vitro suppression.
9 citations