Author

Sean R. Cuddy

University of VirginiaORCID 0000-0002-2062-0691Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

Abigail L. Whitford· 1 shared Aleksandra W. BabnisiD· 1 shared Anna Ruth CliffeiD· 1 shared Daniel A. Engel· 1 shared M. E. FloresiD· 1 shared Marco TiganoiD· 1 shared Patryk A. KrakowiakiD· 1 shared Sara Anna DochnaliD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 36 mutual co-author links

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1 shared paperMicrobiology

Abigail L. Whitford

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1 paper

Recent·Most cited

Co-option of mitochondrial nucleic acid sensing pathways by HSV-1 UL12.5 for reactivation from latent Infection

Patryk A. Krakowiak, M. E. Flores, Sean R. Cuddy, Abigail L. Whitford, Sara Anna Dochnal, Aleksandra W. Babnis, Tsuyoshi Miyake, Marco Tigano, Daniel A. Engel, Anna Ruth Cliffe

This study shows HSV-1 UL12.5 promotes reactivation by inducing mitochondrial nucleic acid sensing, which activates innate immune pathways and supports lytic gene expression during latency exit.

Proceedings of the National Academy of Sciences · Jan 24, 2025Peer-reviewedMicrobiology