Author
The University of Texas at AustinORCID 0000-0002-9210-3343Unclaimed ORCID profile · follow to get notified of new preprints
5 papers
Recent·Most cited
Hao-Yang Liu, Zhengyu Wang, Rahul Sharma…·Jeanne C. Stachowiak
This study shows CD36 and its ligands are internalized via clathrin-mediated endocytosis, not caveolae, and disrupting clathrin inhibits ligand uptake and PROTAC-induced degradation.
Haoyang Liu, Susovan Sarkar, Feng Yuan…·Jeanne C. Stachowiak
This study shows poly-ubiquitylated transmembrane proteins outcompete mono-ubiquitylated and non-ubiquitylated proteins for endocytic uptake by clathrin-coated vesicles.
Susovan Sarkar, Haoyang Liu, Feng Yuan…·Jeanne C. Stachowiak
This study shows Epsin1 stabilizes initiator protein condensation during clathrin-mediated endocytosis only when ubiquitin is present, ensuring cargo-specific vesicle formation.
Caleb D. Swaim, Varun Dwivedi, Yi-Chieh Perng…·Jon M. Huibregtse
6-Thioguanine inhibits SARS-CoV-2 PLpro protease activity and replication in cell cultures at submicromolar concentrations.
Seung Woo Ryu, Rose Stewart, D. Chase Pectol…·Tanya T. Paull
This study identifies HSP70 and HSC70 chaperone clients in human cells using a ubiquitin-mediated tagging strategy, revealing distinct client specificities and stress-induced changes.