Synthetic BiologyProceedings of the National Academy of SciencesPeer-reviewed
A bioengineered probiotic for the oral delivery of a peptide Kv1.3 channel blocker to treat rheumatoid arthritis
Yuqing Wang, Duolong Zhu, Laura Ortiz-Velez…·Christine Beeton
This paper develops a bioengineered probiotic to deliver a Kv1.3 channel blocker peptide for treating rheumatoid arthritis, showing efficacy in reducing inflammation and joint damage in rat models.
32 citations